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LRRTM4 has not been detected as a mutational cancer driver

LRRTM4
Ensembl id ENSG00000176204
Mutated samples
Coding Sequence 142 (2.1%)
Protein Affecting 88 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LRRTM4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 23 20 5.12
Cutaneous melanoma No 27 20 5.42
Lung squamous cell carcinoma No 21 13 7.47
Head and neck squamous cell carcinoma No 12 9 2.40
Esophageal carcinoma No 7 6 4.11
Breast carcinoma No 3 3 0.26
Pancreas adenocarcinoma No 4 3 1.40
Uterine corpus endometrioid carcinoma No 2 2 0.87
Multiple myeloma No 2 2 2.90
Serous ovarian adenocarcinoma No 2 2 0.63
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 3 1 1.02
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Lower grade glioma No 2 1 0.59
Stomach adenocarcinoma No 1 1 0.62
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Prostate adenocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 20 0 0.00
Pylocytic astrocytoma No 5 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence