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LRRN2 has not been detected as a mutational cancer driver

LRRN2
Ensembl id ENSG00000170382
Mutated samples
Coding Sequence 61 (0.9%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LRRN2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 24 19 5.15
Lung adenocarcinoma No 11 9 2.30
Lung squamous cell carcinoma No 4 3 1.72
Esophageal carcinoma No 4 3 2.05
Uterine corpus endometrioid carcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Hepatocarcinoma No 1 1 1.11
Breast carcinoma No 3 1 0.09
Non small cell lung carcinoma No 1 1 3.23
Lower grade glioma No 1 1 0.59
Stomach adenocarcinoma No 3 1 0.62
Small cell lung carcinoma No 2 1 1.45
Glioblastoma multiforme No 1 1 0.26
Bladder carcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence