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LRRC66 has not been detected as a mutational cancer driver

LRRC66
Ensembl id ENSG00000188993
Mutated samples
Coding Sequence 107 (1.6%)
Protein Affecting 81 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LRRC66 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 28 23 6.23
Lung adenocarcinoma No 20 16 4.09
Lung squamous cell carcinoma No 9 7 4.02
Head and neck squamous cell carcinoma No 8 5 1.33
Bladder carcinoma No 4 4 4.08
Renal clear cell carcinoma No 4 4 0.96
Uterine corpus endometrioid carcinoma No 9 4 1.74
Small cell lung carcinoma No 4 4 5.80
Glioblastoma multiforme No 4 3 0.79
Prostate adenocarcinoma No 3 2 0.82
Chronic lymphocytic leukemia No 3 2 0.69
Stomach adenocarcinoma No 3 2 1.24
Esophageal carcinoma No 2 2 1.37
Breast carcinoma No 2 1 0.09
Pancreas adenocarcinoma No 1 1 0.47
Colorectal adenocarcinoma No 1 1 0.44
Multiple myeloma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence