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LRRC52 has not been detected as a mutational cancer driver

LRRC52
Ensembl id ENSG00000162763
Mutated samples
Coding Sequence 37 (0.5%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LRRC52 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 9 7 1.90
Stomach adenocarcinoma No 5 4 2.48
Lung squamous cell carcinoma No 3 2 1.15
Uterine corpus endometrioid carcinoma No 2 2 0.87
Colorectal adenocarcinoma No 2 2 0.87
Lung adenocarcinoma No 3 1 0.26
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 2 1 1.02
Breast carcinoma No 1 1 0.09
Renal clear cell carcinoma No 1 1 0.24
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Serous ovarian adenocarcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence