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LRRC15 has not been detected as a mutational cancer driver

LRRC15
Ensembl id ENSG00000172061
Mutated samples
Coding Sequence 62 (0.9%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LRRC15 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 7 1.90
Lung adenocarcinoma No 9 4 1.02
Serous ovarian adenocarcinoma No 4 4 1.27
Lung squamous cell carcinoma No 5 3 1.72
Head and neck squamous cell carcinoma No 6 3 0.80
Prostate adenocarcinoma No 2 2 0.82
Breast carcinoma No 3 2 0.17
Renal clear cell carcinoma No 2 2 0.48
Hepatocarcinoma No 2 1 1.11
Acute myeloid leukemia No 1 1 0.51
Medulloblastoma No 1 1 0.48
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 2 1 0.43
Stomach adenocarcinoma No 3 1 0.62
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence