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LRP2BP has not been detected as a mutational cancer driver

LRP2BP
Ensembl id ENSG00000109771
Mutated samples
Coding Sequence 31 (0.5%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LRP2BP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 2 2 1.15
Cutaneous melanoma No 4 2 0.54
Lung adenocarcinoma No 2 1 0.26
Bladder carcinoma No 1 1 1.02
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 1 1 0.43
Multiple myeloma No 1 1 1.45
Stomach adenocarcinoma No 1 1 0.62
Head and neck squamous cell carcinoma No 4 1 0.27
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 2 0 0.00
Breast carcinoma No 5 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Thyroid carcinoma No 2 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence