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LRP1B × Head and Neck Squamous Cell Carcinoma ×

LRP1B is detected as a mutational cancer driver in Head and Neck Squamous Cell Carcinoma

LRP1B reports in Head and Neck Squamous Cell Carcinoma (HNSC)

Cancer type details
Head and Neck Squamous Cell Carcinoma
Cohorts 6
Samples 818
Mutations 2,112,343
Driver genes 80
Gene details
LRP1B
Ensembl ID ENSG00000168702
Transcript ID ENST00000389484
Protein ID ENSP00000374135
Cohorts where is driver 2
Mutated samples 100
Mutated samples (%) 12.22
Mutations 179
Mode of action Ambiguous
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence