Top
LRIG1 has not been detected as a mutational cancer driver

LRIG1
Ensembl id ENSG00000144749
Mutated samples
Coding Sequence 84 (1.2%)
Protein Affecting 51 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LRIG1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 25 17 4.61
Lung adenocarcinoma No 4 4 1.02
Bladder carcinoma No 4 4 4.08
Uterine corpus endometrioid carcinoma No 6 4 1.74
Breast carcinoma No 6 3 0.26
Lung squamous cell carcinoma No 6 3 1.72
Renal clear cell carcinoma No 4 3 0.72
Stomach adenocarcinoma No 8 2 1.24
Colorectal adenocarcinoma No 2 2 0.87
Head and neck squamous cell carcinoma No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Pancreas adenocarcinoma No 1 1 0.47
Non small cell lung carcinoma No 2 1 3.23
Serous ovarian adenocarcinoma No 2 1 0.32
Glioblastoma multiforme No 3 1 0.26
Hepatocarcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence