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LRIF1 has not been detected as a mutational cancer driver

LRIF1
Ensembl id ENSG00000121931
Mutated samples
Coding Sequence 54 (0.8%)
Protein Affecting 40 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LRIF1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Head and neck squamous cell carcinoma No 9 8 2.13
Cutaneous melanoma No 12 6 1.63
Lung adenocarcinoma No 4 4 1.02
Lung squamous cell carcinoma No 5 3 1.72
Neuroblastoma No 3 3 1.43
Breast carcinoma No 3 2 0.17
Renal clear cell carcinoma No 4 2 0.48
Stomach adenocarcinoma No 2 2 1.24
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Acute myeloid leukemia No 1 1 0.51
Pancreas adenocarcinoma No 1 1 0.47
Uterine corpus endometrioid carcinoma No 2 1 0.43
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 2 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence