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LPP has not been detected as a mutational cancer driver

LPP
Ensembl id ENSG00000145012
Mutated samples
Coding Sequence 73 (1.1%)
Protein Affecting 40 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LPP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 7 7 1.79
Breast carcinoma No 7 6 0.52
Cutaneous melanoma No 10 5 1.36
Head and neck squamous cell carcinoma No 5 4 1.07
Lung squamous cell carcinoma No 4 3 1.72
Uterine corpus endometrioid carcinoma No 3 3 1.30
Stomach adenocarcinoma No 4 3 1.86
Bladder carcinoma No 2 2 2.04
Colorectal adenocarcinoma No 2 2 0.87
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 1 1 0.31
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 1 0 0.00
Hepatocarcinoma No 5 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 11 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 3 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence