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LPIN1 has not been detected as a mutational cancer driver

LPIN1
Ensembl id ENSG00000134324
Mutated samples
Coding Sequence 69 (1.0%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LPIN1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 12 3.25
Breast carcinoma No 4 4 0.35
Lung squamous cell carcinoma No 4 4 2.30
Renal clear cell carcinoma No 4 4 0.96
Bladder carcinoma No 4 3 3.06
Lung adenocarcinoma No 3 2 0.51
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 4 2 1.24
Small cell lung carcinoma No 2 2 2.90
Head and neck squamous cell carcinoma No 3 2 0.53
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Medulloblastoma No 2 1 0.48
Uterine corpus endometrioid carcinoma No 2 1 0.43
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Hepatocarcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence