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LNX1 has not been detected as a mutational cancer driver

LNX1
Ensembl id ENSG00000072201
Mutated samples
Coding Sequence 64 (0.9%)
Protein Affecting 37 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LNX1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 19 16 4.34
Breast carcinoma No 6 4 0.35
Lung adenocarcinoma No 3 3 0.77
Uterine corpus endometrioid carcinoma No 3 3 1.30
Chronic lymphocytic leukemia No 7 2 0.69
Stomach adenocarcinoma No 4 2 1.24
Bladder carcinoma No 1 1 1.02
Acute myeloid leukemia No 2 1 0.51
Lung squamous cell carcinoma No 2 1 0.57
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 2 0 0.00
Hepatocarcinoma No 2 0 0.00
Lower grade glioma No 1 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 3 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence