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LHCGR has not been detected as a mutational cancer driver

LHCGR
Ensembl id ENSG00000138039
Mutated samples
Coding Sequence 166 (2.4%)
Protein Affecting 86 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LHCGR gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 53 30 8.13
Breast carcinoma No 12 9 0.78
Stomach adenocarcinoma No 14 8 4.97
Lung squamous cell carcinoma No 21 7 4.02
Lung adenocarcinoma No 13 6 1.53
Uterine corpus endometrioid carcinoma No 5 5 2.17
Head and neck squamous cell carcinoma No 7 4 1.07
Esophageal carcinoma No 7 4 2.74
Serous ovarian adenocarcinoma No 5 3 0.95
Colorectal adenocarcinoma No 6 3 1.31
Pancreas adenocarcinoma No 3 2 0.93
Glioblastoma multiforme No 3 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 2 1 1.02
Small cell lung carcinoma No 5 1 1.45
Hepatocarcinoma No 4 0 0.00
Acute myeloid leukemia No 1 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence