IntOGen - LDB1 gene cancer mutations

LDB1 is detected as a mutational cancer driver

LDB1 reports

Methods
Mutation distribution

Gene details

LDB1
Ensembl ID ENSG00000198728 Transcript ID ENST00000673968 Protein ID ENSP00000501277
Cancer types where is driver 2 Cohorts where is driver 3 Mutated samples 12 Mutations 171
Mode of action Loss of function
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence