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LCE2B has not been detected as a mutational cancer driver

LCE2B
Ensembl id ENSG00000159455
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 20 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all LCE2B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 9 4 1.02
Breast carcinoma No 3 3 0.26
Cutaneous melanoma No 9 3 0.81
Lung squamous cell carcinoma No 3 2 1.15
Stomach adenocarcinoma No 4 2 1.24
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 1 1 1.02
Uterine corpus endometrioid carcinoma No 6 1 0.43
Lower grade glioma No 2 1 0.59
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 2 1 0.68
Chronic lymphocytic leukemia No 1 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 3 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence