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KRAS is detected as a mutational cancer driver in 2 Lung adenocarcinoma projects

Lung adenocarcinoma
Projects 2
391 Samples
Coding sequence mutations (CSMs)
in driver genes 1564
in all genes 112729
Protein affecting mutations (PAMs)
in driver genes 1381
in all genes 61402
KRAS
Ensembl id ENSG00000133703
Mutated samples
Coding Sequence 121 (30.9%)
Protein Affecting 120 (30.7%)
Mode of action Activating
Known driver Yes
Project Signals
LUAD_WUSTL FC
LUAD_TCGA RFC
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Lung adenocarcinoma projects in all KRAS gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma Washington University Yes 60 60 15.35
Lung adenocarcinoma TCGA Yes 61 60 15.35
The mutations needle plot shows the distribution of the observed KRAS cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification