KMT2D is detected as a mutational cancer driver
KMT2D reports
Gene details
KMT2D |
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Ensembl ID
ENSG00000167548
Transcript ID ENST00000301067 Protein ID ENSP00000301067 |
Cancer types where is driver
37
Cohorts where is driver 86 Mutated samples 1,312 Mutations 3,064 |
Mode of action Ambiguous |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BLCA (Bladder Urothelial Carcinoma) | 49824 | 2057 | 4.13 |
CESC (Cervical Squamous Cell Carcinoma) | 49824 | 1850 | 3.71 |
DLBCL (Diffuse Large B-Cell Lymphoma, NOS) | 49824 | 2057 | 4.13 |
HNSC (Head and Neck Squamous Cell Carcinoma) | 49824 | 1993 | 4.00 |
LY (Lymphoid Neoplasm) | 49824 | 2057 | 4.13 |
LUNG_CANCER (Lung) | 49824 | 1930 | 3.87 |
LUSC (Lung Squamous Cell Carcinoma) | 49824 | 1972 | 3.96 |
PRAD (Prostate Adenocarcinoma) | 49824 | 1850 | 3.71 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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