Top
KLF7 has not been detected as a mutational cancer driver

KLF7
Ensembl id ENSG00000118263
Mutated samples
Coding Sequence 28 (0.4%)
Protein Affecting 17 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KLF7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 8 5 1.36
Breast carcinoma No 2 2 0.17
Stomach adenocarcinoma No 2 2 1.24
Small cell lung carcinoma No 2 2 2.90
Lung adenocarcinoma No 1 1 0.26
Hepatocarcinoma No 2 1 1.11
Lung squamous cell carcinoma No 1 1 0.57
Neuroblastoma No 1 1 0.48
Head and neck squamous cell carcinoma No 2 1 0.27
Glioblastoma multiforme No 1 1 0.26
Renal clear cell carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence