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KIF9 has not been detected as a mutational cancer driver

KIF9
Ensembl id ENSG00000088727
Mutated samples
Coding Sequence 48 (0.7%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KIF9 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 8 7 1.79
Cutaneous melanoma No 9 5 1.36
Lung squamous cell carcinoma No 5 4 2.30
Head and neck squamous cell carcinoma No 5 4 1.07
Breast carcinoma No 2 2 0.17
Medulloblastoma No 2 2 0.95
Uterine corpus endometrioid carcinoma No 2 2 0.87
Stomach adenocarcinoma No 3 2 1.24
Colorectal adenocarcinoma No 2 2 0.87
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Non small cell lung carcinoma No 2 1 3.23
Multiple myeloma No 1 1 1.45
Small cell lung carcinoma No 1 1 1.45
Glioblastoma multiforme No 2 1 0.26
Lower grade glioma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence