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KIF26B has not been detected as a mutational cancer driver

KIF26B
Ensembl id ENSG00000162849
Mutated samples
Coding Sequence 151 (2.2%)
Protein Affecting 89 (1.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KIF26B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 41 18 4.88
Breast carcinoma No 20 14 1.22
Uterine corpus endometrioid carcinoma No 12 10 4.35
Lung adenocarcinoma No 12 9 2.30
Head and neck squamous cell carcinoma No 12 9 2.40
Serous ovarian adenocarcinoma No 5 4 1.27
Esophageal carcinoma No 5 4 2.74
Medulloblastoma No 3 3 1.43
Stomach adenocarcinoma No 5 3 1.86
Bladder carcinoma No 4 2 2.04
Lung squamous cell carcinoma No 2 2 1.15
Renal clear cell carcinoma No 3 2 0.48
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 3 2 0.87
Hepatocarcinoma No 2 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Neuroblastoma No 1 1 0.48
Lower grade glioma No 2 1 0.59
Glioblastoma multiforme No 1 1 0.26
Prostate adenocarcinoma No 3 0 0.00
Chronic lymphocytic leukemia No 9 0 0.00
Multiple myeloma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence