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KIAA1614 has not been detected as a mutational cancer driver

KIAA1614
Ensembl id ENSG00000135835
Mutated samples
Coding Sequence 72 (1.1%)
Protein Affecting 50 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KIAA1614 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 20 15 4.07
Lung adenocarcinoma No 7 6 1.53
Uterine corpus endometrioid carcinoma No 7 5 2.17
Serous ovarian adenocarcinoma No 5 5 1.58
Breast carcinoma No 6 4 0.35
Lung squamous cell carcinoma No 3 3 1.72
Renal clear cell carcinoma No 3 3 0.72
Head and neck squamous cell carcinoma No 4 3 0.80
Prostate adenocarcinoma No 3 2 0.82
Esophageal carcinoma No 4 2 1.37
Stomach adenocarcinoma No 3 1 0.62
Glioblastoma multiforme No 2 1 0.26
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
Small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence