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KIAA1324 has not been detected as a mutational cancer driver

KIAA1324
Ensembl id ENSG00000116299
Mutated samples
Coding Sequence 62 (0.9%)
Protein Affecting 42 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KIAA1324 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 27 19 5.15
Lung adenocarcinoma No 5 5 1.28
Breast carcinoma No 5 5 0.44
Head and neck squamous cell carcinoma No 2 2 0.53
Esophageal carcinoma No 2 2 1.37
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 2 1 1.02
Lung squamous cell carcinoma No 1 1 0.57
Uterine corpus endometrioid carcinoma No 2 1 0.43
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 3 1 0.32
Stomach adenocarcinoma No 2 1 0.62
Glioblastoma multiforme No 1 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Chronic lymphocytic leukemia No 3 0 0.00
Multiple myeloma No 2 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence