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KIAA0754 has not been detected as a mutational cancer driver

KIAA0754
Ensembl id ENSG00000255103
Mutated samples
Coding Sequence 69 (1.0%)
Protein Affecting 59 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KIAA0754 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 10 2.71
Lung adenocarcinoma No 6 6 1.53
Bladder carcinoma No 9 6 6.12
Prostate adenocarcinoma No 5 5 2.06
Breast carcinoma No 5 5 0.44
Lung squamous cell carcinoma No 5 5 2.87
Renal clear cell carcinoma No 6 5 1.20
Head and neck squamous cell carcinoma No 5 4 1.07
Stomach adenocarcinoma No 3 3 1.86
Uterine corpus endometrioid carcinoma No 3 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Esophageal carcinoma No 2 2 1.37
Medulloblastoma No 1 1 0.48
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Diffuse B cell lymphoma No 1 1 4.35
Hepatocarcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence