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KCTD3 has not been detected as a mutational cancer driver

KCTD3
Ensembl id ENSG00000136636
Mutated samples
Coding Sequence 60 (0.9%)
Protein Affecting 51 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KCTD3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 12 11 2.81
Breast carcinoma No 9 9 0.78
Cutaneous melanoma No 10 8 2.17
Lung squamous cell carcinoma No 5 5 2.87
Head and neck squamous cell carcinoma No 5 5 1.33
Hepatocarcinoma No 3 2 2.22
Non small cell lung carcinoma No 2 2 6.45
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 3 2 1.24
Small cell lung carcinoma No 2 2 2.90
Bladder carcinoma No 1 1 1.02
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 2 1 0.43
Thyroid carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence