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KCNT2 has not been detected as a mutational cancer driver

KCNT2
Ensembl id ENSG00000162687
Mutated samples
Coding Sequence 217 (3.2%)
Protein Affecting 166 (2.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KCNT2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 64 50 13.55
Lung adenocarcinoma No 27 25 6.39
Head and neck squamous cell carcinoma No 18 17 4.53
Lung squamous cell carcinoma No 14 11 6.32
Breast carcinoma No 10 10 0.87
Esophageal carcinoma No 12 10 6.85
Stomach adenocarcinoma No 10 9 5.59
Colorectal adenocarcinoma No 8 6 2.62
Prostate adenocarcinoma No 3 3 1.23
Uterine corpus endometrioid carcinoma No 5 3 1.30
Multiple myeloma No 3 3 4.35
Serous ovarian adenocarcinoma No 4 3 0.95
Small cell lung carcinoma No 5 3 4.35
Renal clear cell carcinoma No 2 2 0.48
Non small cell lung carcinoma No 4 2 6.45
Chronic lymphocytic leukemia No 15 2 0.69
Glioblastoma multiforme No 2 2 0.53
Hepatocarcinoma No 1 1 1.11
Bladder carcinoma No 3 1 1.02
Acute myeloid leukemia No 1 1 0.51
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Pylocytic astrocytoma No 4 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence