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KCNJ3 has not been detected as a mutational cancer driver

KCNJ3
Ensembl id ENSG00000162989
Mutated samples
Coding Sequence 115 (1.7%)
Protein Affecting 82 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KCNJ3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 34 27 7.32
Lung adenocarcinoma No 20 13 3.32
Lung squamous cell carcinoma No 9 9 5.17
Stomach adenocarcinoma No 6 6 3.73
Small cell lung carcinoma No 5 5 7.25
Breast carcinoma No 5 4 0.35
Head and neck squamous cell carcinoma No 8 4 1.07
Renal clear cell carcinoma No 3 3 0.72
Uterine corpus endometrioid carcinoma No 4 3 1.30
Esophageal carcinoma No 3 3 2.05
Colorectal adenocarcinoma No 3 2 0.87
Bladder carcinoma No 1 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Glioblastoma multiforme No 2 1 0.26
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 9 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence