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KANK4 has not been detected as a mutational cancer driver

KANK4
Ensembl id ENSG00000132854
Mutated samples
Coding Sequence 105 (1.5%)
Protein Affecting 80 (1.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all KANK4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 40 34 9.21
Lung adenocarcinoma No 15 11 2.81
Lung squamous cell carcinoma No 7 4 2.30
Renal clear cell carcinoma No 5 4 0.96
Uterine corpus endometrioid carcinoma No 4 4 1.74
Prostate adenocarcinoma No 3 3 1.23
Head and neck squamous cell carcinoma No 5 3 0.80
Breast carcinoma No 3 2 0.17
Medulloblastoma No 2 2 0.95
Non small cell lung carcinoma No 2 2 6.45
Stomach adenocarcinoma No 3 2 1.24
Glioblastoma multiforme No 2 2 0.53
Bladder carcinoma No 2 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 3 1 0.32
Colorectal adenocarcinoma No 3 1 0.44
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence