IntOGen - JUN gene cancer mutations

JUN is detected as a mutational cancer driver

JUN reports

Methods
Mutation distribution

Gene details

JUN
Ensembl ID ENSG00000177606 Transcript ID ENST00000371222 Protein ID ENSP00000360266
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 9 Mutations 122
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence