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ITSN2 has not been detected as a mutational cancer driver

ITSN2
Ensembl id ENSG00000198399
Mutated samples
Coding Sequence 97 (1.4%)
Protein Affecting 69 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ITSN2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Breast carcinoma No 12 11 0.96
Cutaneous melanoma No 19 11 2.98
Head and neck squamous cell carcinoma No 10 9 2.40
Stomach adenocarcinoma No 6 6 3.73
Lung adenocarcinoma No 6 5 1.28
Bladder carcinoma No 5 5 5.10
Lung squamous cell carcinoma No 6 4 2.30
Renal clear cell carcinoma No 7 3 0.72
Uterine corpus endometrioid carcinoma No 3 3 1.30
Prostate adenocarcinoma No 2 2 0.82
Hepatocarcinoma No 5 2 2.22
Small cell lung carcinoma No 2 2 2.90
Pancreas adenocarcinoma No 2 1 0.47
Chronic lymphocytic leukemia No 3 1 0.34
Serous ovarian adenocarcinoma No 2 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 2 1 0.26
Acute lymphocytic leukemia No 1 1 0.82
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence