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ITLN1 has not been detected as a mutational cancer driver

ITLN1
Ensembl id ENSG00000179914
Mutated samples
Coding Sequence 46 (0.7%)
Protein Affecting 31 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ITLN1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 17 12 3.25
Lung adenocarcinoma No 5 4 1.02
Prostate adenocarcinoma No 3 2 0.82
Lung squamous cell carcinoma No 2 2 1.15
Glioblastoma multiforme No 2 2 0.53
Breast carcinoma No 3 1 0.09
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 1 1 0.43
Chronic lymphocytic leukemia No 2 1 0.34
Multiple myeloma No 1 1 1.45
Lower grade glioma No 2 1 0.59
Serous ovarian adenocarcinoma No 2 1 0.32
Stomach adenocarcinoma No 1 1 0.62
Head and neck squamous cell carcinoma No 2 1 0.27
Pancreas adenocarcinoma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence