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ITGAV has not been detected as a mutational cancer driver

ITGAV
Ensembl id ENSG00000138448
Mutated samples
Coding Sequence 69 (1.0%)
Protein Affecting 45 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ITGAV gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 13 8 2.17
Lung adenocarcinoma No 7 6 1.53
Breast carcinoma No 8 6 0.52
Stomach adenocarcinoma No 5 4 2.48
Head and neck squamous cell carcinoma No 6 4 1.07
Lung squamous cell carcinoma No 5 3 1.72
Bladder carcinoma No 4 2 2.04
Uterine corpus endometrioid carcinoma No 2 2 0.87
Serous ovarian adenocarcinoma No 2 2 0.63
Colorectal adenocarcinoma No 2 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 3 1 1.11
Acute myeloid leukemia No 1 1 0.51
Multiple myeloma No 1 1 1.45
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Medulloblastoma No 1 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Thyroid carcinoma No 1 0 0.00
Pylocytic astrocytoma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence