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IQGAP3 has not been detected as a mutational cancer driver

IQGAP3
Ensembl id ENSG00000183856
Mutated samples
Coding Sequence 106 (1.6%)
Protein Affecting 71 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all IQGAP3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 29 19 5.15
Lung squamous cell carcinoma No 12 10 5.75
Breast carcinoma No 8 7 0.61
Stomach adenocarcinoma No 5 5 3.11
Head and neck squamous cell carcinoma No 7 5 1.33
Lung adenocarcinoma No 7 4 1.02
Small cell lung carcinoma No 4 4 5.80
Uterine corpus endometrioid carcinoma No 6 3 1.30
Colorectal adenocarcinoma No 4 3 1.31
Glioblastoma multiforme No 6 3 0.79
Bladder carcinoma No 3 2 2.04
Renal clear cell carcinoma No 3 2 0.48
Serous ovarian adenocarcinoma No 5 2 0.63
Esophageal carcinoma No 3 2 1.37
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Multiple myeloma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence