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INTS3 has not been detected as a mutational cancer driver

INTS3
Ensembl id ENSG00000143624
Mutated samples
Coding Sequence 81 (1.2%)
Protein Affecting 38 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all INTS3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 8 2.17
Stomach adenocarcinoma No 10 6 3.73
Uterine corpus endometrioid carcinoma No 7 4 1.74
Lung adenocarcinoma No 7 3 0.77
Bladder carcinoma No 5 3 3.06
Breast carcinoma No 6 3 0.26
Lung squamous cell carcinoma No 3 2 1.15
Hepatocarcinoma No 1 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Thyroid carcinoma No 1 1 0.31
Chronic lymphocytic leukemia No 3 1 0.34
Lower grade glioma No 1 1 0.59
Serous ovarian adenocarcinoma No 3 1 0.32
Colorectal adenocarcinoma No 1 1 0.44
Head and neck squamous cell carcinoma No 3 1 0.27
Esophageal carcinoma No 2 1 0.68
Prostate adenocarcinoma No 1 0 0.00
Renal clear cell carcinoma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence