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INSRR has not been detected as a mutational cancer driver

INSRR
Ensembl id ENSG00000027644
Mutated samples
Coding Sequence 126 (1.9%)
Protein Affecting 96 (1.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all INSRR gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 39 26 7.05
Lung adenocarcinoma No 21 19 4.86
Breast carcinoma No 13 12 1.05
Uterine corpus endometrioid carcinoma No 10 7 3.04
Lung squamous cell carcinoma No 6 5 2.87
Serous ovarian adenocarcinoma No 6 5 1.58
Esophageal carcinoma No 5 5 3.42
Renal clear cell carcinoma No 4 4 0.96
Bladder carcinoma No 4 3 3.06
Stomach adenocarcinoma No 3 3 1.86
Colorectal adenocarcinoma No 2 2 0.87
Prostate adenocarcinoma No 2 1 0.41
Pylocytic astrocytoma No 1 1 0.99
Small cell lung carcinoma No 1 1 1.45
Head and neck squamous cell carcinoma No 2 1 0.27
Glioblastoma multiforme No 2 1 0.26
Pancreas adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Lower grade glioma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence