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INPP5B has not been detected as a mutational cancer driver

INPP5B
Ensembl id ENSG00000204084
Mutated samples
Coding Sequence 63 (0.9%)
Protein Affecting 36 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all INPP5B gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 8 6 3.45
Cutaneous melanoma No 15 6 1.63
Breast carcinoma No 7 4 0.35
Head and neck squamous cell carcinoma No 6 3 0.80
Lung adenocarcinoma No 4 2 0.51
Hepatocarcinoma No 3 2 2.22
Renal clear cell carcinoma No 3 2 0.48
Stomach adenocarcinoma No 3 2 1.24
Small cell lung carcinoma No 3 2 2.90
Prostate adenocarcinoma No 1 1 0.41
Bladder carcinoma No 2 1 1.02
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 2 1 0.43
Serous ovarian adenocarcinoma No 1 1 0.32
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 1 1 0.68
Thyroid carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence