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IL23R has not been detected as a mutational cancer driver

IL23R
Ensembl id ENSG00000162594
Mutated samples
Coding Sequence 40 (0.6%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all IL23R gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 10 2.71
Breast carcinoma No 4 4 0.35
Bladder carcinoma No 2 2 2.04
Lung squamous cell carcinoma No 3 2 1.15
Stomach adenocarcinoma No 2 2 1.24
Lung adenocarcinoma No 3 1 0.26
Hepatocarcinoma No 2 1 1.11
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 1 1 0.31
Uterine corpus endometrioid carcinoma No 1 1 0.43
Lower grade glioma No 1 1 0.59
Head and neck squamous cell carcinoma No 1 1 0.27
Esophageal carcinoma No 1 1 0.68
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 2 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence