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IGSF11 has not been detected as a mutational cancer driver

IGSF11
Ensembl id ENSG00000144847
Mutated samples
Coding Sequence 98 (1.4%)
Protein Affecting 32 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all IGSF11 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung squamous cell carcinoma No 15 6 3.45
Lung adenocarcinoma No 13 5 1.28
Breast carcinoma No 9 3 0.26
Cutaneous melanoma No 17 3 0.81
Non small cell lung carcinoma No 3 3 9.68
Head and neck squamous cell carcinoma No 7 3 0.80
Renal clear cell carcinoma No 3 2 0.48
Bladder carcinoma No 2 1 1.02
Neuroblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 5 1 0.34
Stomach adenocarcinoma No 4 1 0.62
Small cell lung carcinoma No 4 1 1.45
Colorectal adenocarcinoma No 5 1 0.44
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 3 0 0.00
Uterine corpus endometrioid carcinoma No 2 0 0.00
Lower grade glioma No 1 0 0.00
Serous ovarian adenocarcinoma No 2 0 0.00
Glioblastoma multiforme No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence