Top
HYAL3 has not been detected as a mutational cancer driver

HYAL3
Ensembl id ENSG00000186792
Mutated samples
Coding Sequence 77 (1.1%)
Protein Affecting 14 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HYAL3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Prostate adenocarcinoma No 3 2 0.82
Lung adenocarcinoma No 8 2 0.51
Lung squamous cell carcinoma No 6 2 1.15
Stomach adenocarcinoma No 4 2 1.24
Bladder carcinoma No 5 1 1.02
Cutaneous melanoma No 18 1 0.27
Uterine corpus endometrioid carcinoma No 5 1 0.43
Chronic lymphocytic leukemia No 3 1 0.34
Serous ovarian adenocarcinoma No 4 1 0.32
Head and neck squamous cell carcinoma No 7 1 0.27
Breast carcinoma No 6 0 0.00
Renal clear cell carcinoma No 1 0 0.00
Lower grade glioma No 2 0 0.00
Small cell lung carcinoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Glioblastoma multiforme No 1 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence