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HSD11B1 has not been detected as a mutational cancer driver

HSD11B1
Ensembl id ENSG00000117594
Mutated samples
Coding Sequence 32 (0.5%)
Protein Affecting 26 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HSD11B1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 11 2.98
Breast carcinoma No 3 3 0.26
Lung squamous cell carcinoma No 3 3 1.72
Lung adenocarcinoma No 3 2 0.51
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 1 1 0.41
Uterine corpus endometrioid carcinoma No 3 1 0.43
Lower grade glioma No 1 1 0.59
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence