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HOXD13 has not been detected as a mutational cancer driver

HOXD13
Ensembl id ENSG00000128714
Mutated samples
Coding Sequence 49 (0.7%)
Protein Affecting 17 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HOXD13 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 7 4 1.08
Head and neck squamous cell carcinoma No 8 3 0.80
Esophageal carcinoma No 4 3 2.05
Breast carcinoma No 3 2 0.17
Small cell lung carcinoma No 3 2 2.90
Lung adenocarcinoma No 6 1 0.26
Bladder carcinoma No 2 1 1.02
Chronic lymphocytic leukemia No 1 1 0.34
Prostate adenocarcinoma No 1 0 0.00
Medulloblastoma No 1 0 0.00
Lung squamous cell carcinoma No 4 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Thyroid carcinoma No 2 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
Serous ovarian adenocarcinoma No 1 0 0.00
Stomach adenocarcinoma No 3 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence