HLA-B is detected as a mutational cancer driver
HLA-B reports
Gene details
HLA-B |
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Ensembl ID
ENSG00000234745
Transcript ID ENST00000412585 Protein ID ENSP00000399168 |
Cancer types where is driver
6
Cohorts where is driver 7 Mutated samples 51 Mutations 463 |
Mode of action Loss of function |
Known driver False |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
DLBCL (Diffuse Large B-Cell Lymphoma, NOS) | 3249 | 1019 | 31.36 |
LY (Lymphoid Neoplasm) | 3249 | 999 | 30.75 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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