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HIVEP3 has not been detected as a mutational cancer driver

HIVEP3
Ensembl id ENSG00000127124
Mutated samples
Coding Sequence 170 (2.5%)
Protein Affecting 123 (1.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HIVEP3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 58 41 11.11
Lung adenocarcinoma No 12 10 2.56
Stomach adenocarcinoma No 14 10 6.21
Uterine corpus endometrioid carcinoma No 12 9 3.91
Lung squamous cell carcinoma No 10 8 4.60
Breast carcinoma No 10 7 0.61
Head and neck squamous cell carcinoma No 9 7 1.87
Bladder carcinoma No 4 4 4.08
Serous ovarian adenocarcinoma No 4 4 1.27
Colorectal adenocarcinoma No 5 4 1.75
Esophageal carcinoma No 4 4 2.74
Renal clear cell carcinoma No 4 3 0.72
Lower grade glioma No 5 3 1.78
Small cell lung carcinoma No 4 3 4.35
Multiple myeloma No 2 2 2.90
Prostate adenocarcinoma No 1 1 0.41
Thyroid carcinoma No 2 1 0.31
Non small cell lung carcinoma No 1 1 3.23
Glioblastoma multiforme No 2 1 0.26
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence