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HHIPL2 has not been detected as a mutational cancer driver

HHIPL2
Ensembl id ENSG00000143512
Mutated samples
Coding Sequence 105 (1.5%)
Protein Affecting 76 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HHIPL2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 43 28 7.59
Lung adenocarcinoma No 13 10 2.56
Lung squamous cell carcinoma No 9 8 4.60
Head and neck squamous cell carcinoma No 7 6 1.60
Glioblastoma multiforme No 6 5 1.32
Bladder carcinoma No 3 3 3.06
Breast carcinoma No 3 3 0.26
Renal clear cell carcinoma No 4 3 0.72
Small cell lung carcinoma No 3 3 4.35
Uterine corpus endometrioid carcinoma No 4 2 0.87
Colorectal adenocarcinoma No 2 2 0.87
Prostate adenocarcinoma No 1 1 0.41
Serous ovarian adenocarcinoma No 1 1 0.32
Stomach adenocarcinoma No 1 1 0.62
Hepatocarcinoma No 1 0 0.00
Thyroid carcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence