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HHIP has not been detected as a mutational cancer driver

HHIP
Ensembl id ENSG00000164161
Mutated samples
Coding Sequence 65 (1.0%)
Protein Affecting 52 (0.8%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HHIP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 29 25 6.78
Lung squamous cell carcinoma No 3 3 1.72
Uterine corpus endometrioid carcinoma No 3 3 1.30
Prostate adenocarcinoma No 2 2 0.82
Hepatocarcinoma No 3 2 2.22
Renal clear cell carcinoma No 4 2 0.48
Serous ovarian adenocarcinoma No 2 2 0.63
Stomach adenocarcinoma No 3 2 1.24
Small cell lung carcinoma No 3 2 2.90
Glioblastoma multiforme No 2 2 0.53
Esophageal carcinoma No 3 2 1.37
Lung adenocarcinoma No 1 1 0.26
Non small cell lung carcinoma No 1 1 3.23
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Head and neck squamous cell carcinoma No 1 1 0.27
Bladder carcinoma No 1 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence