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HECW2 has not been detected as a mutational cancer driver

HECW2
Ensembl id ENSG00000138411
Mutated samples
Coding Sequence 171 (2.5%)
Protein Affecting 128 (1.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HECW2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 55 44 11.92
Head and neck squamous cell carcinoma No 12 12 3.20
Lung adenocarcinoma No 13 11 2.81
Breast carcinoma No 12 11 0.96
Lung squamous cell carcinoma No 12 11 6.32
Stomach adenocarcinoma No 14 10 6.21
Small cell lung carcinoma No 8 7 10.14
Uterine corpus endometrioid carcinoma No 6 4 1.74
Colorectal adenocarcinoma No 7 4 1.75
Bladder carcinoma No 4 3 3.06
Renal clear cell carcinoma No 3 2 0.48
Serous ovarian adenocarcinoma No 5 2 0.63
Hepatocarcinoma No 2 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Non small cell lung carcinoma No 2 1 3.23
Lower grade glioma No 1 1 0.59
Pylocytic astrocytoma No 3 1 0.99
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 2 1 0.68
Chronic lymphocytic leukemia No 7 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence