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HDAC4 is detected as a mutational cancer driver

HDAC4 reports

Gene details
HDAC4
Ensembl ID ENSG00000068024
Transcript ID ENST00000345617
Protein ID ENSP00000264606
Cancer types where is driver 2
Cohorts where is driver 2
Mutated samples 13
Mutations 479
Mode of action Activating
Known driver False
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence