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HADHA has not been detected as a mutational cancer driver

HADHA
Ensembl id ENSG00000084754
Mutated samples
Coding Sequence 43 (0.6%)
Protein Affecting 28 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all HADHA gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 8 8 2.17
Head and neck squamous cell carcinoma No 3 3 0.80
Lung adenocarcinoma No 2 2 0.51
Lung squamous cell carcinoma No 3 2 1.15
Uterine corpus endometrioid carcinoma No 4 2 0.87
Bladder carcinoma No 1 1 1.02
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Thyroid carcinoma No 1 1 0.31
Neuroblastoma No 1 1 0.48
Non small cell lung carcinoma No 3 1 3.23
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 1 1 0.26
Esophageal carcinoma No 1 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Breast carcinoma No 5 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Multiple myeloma No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence