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GRM7 has not been detected as a mutational cancer driver

GRM7
Ensembl id ENSG00000196277
Mutated samples
Coding Sequence 187 (2.8%)
Protein Affecting 114 (1.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GRM7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 67 36 9.76
Lung adenocarcinoma No 17 13 3.32
Head and neck squamous cell carcinoma No 11 9 2.40
Lung squamous cell carcinoma No 9 8 4.60
Stomach adenocarcinoma No 8 7 4.35
Colorectal adenocarcinoma No 8 7 3.06
Breast carcinoma No 7 5 0.44
Bladder carcinoma No 4 4 4.08
Uterine corpus endometrioid carcinoma No 6 4 1.74
Serous ovarian adenocarcinoma No 4 4 1.27
Esophageal carcinoma No 7 4 2.74
Chronic lymphocytic leukemia No 21 3 1.03
Prostate adenocarcinoma No 2 2 0.82
Lower grade glioma No 3 2 1.18
Small cell lung carcinoma No 2 2 2.90
Glioblastoma multiforme No 2 2 0.53
Renal clear cell carcinoma No 1 1 0.24
Non small cell lung carcinoma No 1 1 3.23
Hepatocarcinoma No 1 0 0.00
Acute myeloid leukemia No 1 0 0.00
Pylocytic astrocytoma No 3 0 0.00
Diffuse B cell lymphoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence