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GRK7 has not been detected as a mutational cancer driver

GRK7
Ensembl id ENSG00000114124
Mutated samples
Coding Sequence 53 (0.8%)
Protein Affecting 37 (0.5%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GRK7 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 23 17 4.61
Lung squamous cell carcinoma No 6 5 2.87
Lung adenocarcinoma No 5 4 1.02
Stomach adenocarcinoma No 5 4 2.48
Breast carcinoma No 2 2 0.17
Uterine corpus endometrioid carcinoma No 1 1 0.43
Chronic lymphocytic leukemia No 1 1 0.34
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Hepatocarcinoma No 1 0 0.00
Bladder carcinoma No 1 0 0.00
Head and neck squamous cell carcinoma No 2 0 0.00
Glioblastoma multiforme No 2 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence