GPSM2 mutations in 4 cancer types possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Lung adenocarcinoma, Lung squamous cell carcinoma, Uterine corpus endometrioid carcinoma, Head and neck squamous cell carcinoma

Ensembl id ENSG00000121957
Mutated samples
Coding Sequence 41 (0.6%)
Protein Affecting 26 (0.4%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GPSM2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma Yes 2 2 0.51
Lung squamous cell carcinoma Yes 2 2 1.15
Uterine corpus endometrioid carcinoma Yes 3 2 0.87
Head and neck squamous cell carcinoma Yes 3 2 0.53
Breast carcinoma No 7 7 0.61
Cutaneous melanoma No 14 6 1.63
Hepatocarcinoma No 2 1 1.11
Bladder carcinoma No 1 1 1.02
Renal clear cell carcinoma No 2 1 0.24
Stomach adenocarcinoma No 2 1 0.62
Glioblastoma multiforme No 2 1 0.26
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence